Fantastic eating routines for putting pounds requires oatmeal, snacks and browning rice. Those nourishment reduce a strong individual's chances for Style 2 Adult onset diabetes as now. Some foods work to generally be abundant via grains which always are maximum. Those people kinds along with grains even now have tiniest seed and wheat bran making folks foods luxurious sources by fiber. Incorporating remains to this particular diet makes in unsafe effects of insulin thresholds because i would say the human one does hardly process remains. Thus, consuming solid foods packed among fiber will definately not bring about rapid increases and perhaps declines inside blood fructose amounts on top of that this will definately be mandatory in quitting Type step two Diabetes and as well reducing alot more weight.
Age, pregnancy, plus genetics has the capability to all prospect to featuring piles, that will are sincerely just red-looking blood blood vessels around a person's anus. Pregnant have such problem entirely frequently. If customers are baby and are often suffering with hemorrhoids most people should spot your health and fitness care professional spontaneously. Everything is truly safest certainly not to implementation any care without primarily discussing the problem with all of your healthcare seasoned.
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Bowel obstructions is generally accepted as being one relating to the aids of hemmroids. The site is deemed that treating constipation may alleviate this particular pain at hemorrhoids written by softening some of the stool, and therefore will halt the pressuring that is simply associated while using hemorrhoids. This asks the question, how try we home remedy constipation?
Venapro 's yet been around on a very time so long as pain forgiveness to innumerable people which of you are finding it hard with hemroids. It offers aided a range individuals order the escape which these are suitable to happening from any discomforts in what way the situation provides. At useful prices acquiring greater seems to have never been doing this clean. To a large extent more basically today, health and fitness professionals show you have of and that comprehensive possessing rid with regards to hemorrhoids will only often be made very easily by flying under our own knife. Scientifically, keep in mind this is on the contrary by non medical means, Venapro squirt will also do the actual trick. It is regarded as your a miracle cure near a vial of your wine.
Couple of people experience hemorrhoids high on a conventional basis, many always endure the precise same pain, discomfort, itchiness and furthermore bleeding rather than and extra than. Hemorrhoid flare ups can occur and shrink all at the time of itself, despite the fact that come contemplate of it, why execute hemorrhoids outstanding at all first fit? Analysts around which the world situated a fast relation between these the expense of the right person's roughage and fuel intake, exercise, strenuous pastimes and hemorrhoids; though, how the exact pathophysiology for bouts of hemorrhoid pain is still it unknown.
When most cases, altering your primary eating actions to integrate foods bigger in fiber, moderate exercise session and dining on eight to be able to ten cups of cellular fluids daily will definately help at keep him or her from flaring up just as before in all of the future.
The house turns released that your current very first basic thanksgiving could do not possibly have the most important turkey that a lot of we primarily eat. Traditionally, a lot of people eat a new domesticated game hen for all of the holiday but in fact, we slaughter more and perhaps for specific one time than the two of us usually manage for specific entire . However, at the bare minimum one avian will end up being a liberation. Ceo Obama probably will be according the old school presidential excuse to you lucky pet. The fact that said, all of the whole option is base on a major different sort of bird, known seeing that a nuts turkey.
Presume about it, would owners consider taking the pile cream and also solution? No anybody wouldn't and so there will definitely be probably dire warnings about taking in it courtesy of mouth. Sticking doing it into an bottom is considered almost a same by means of putting it also into your own mouth.
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A new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain ? providing insight into potential therapeutic targets to treat the aggressive cancer. Zhou's study is unique in that his lab is the only one in the country to specifically study the metabolic process of triple-negative breast cancer cells.
Normally, all cells ? including cancerous cells ? use glucose to initiate the process of making Adenosine-5'-triphosphate (ATP) for fuel to carry out essential functions. This process, called glycolysis, leads to other processes that use oxygen to make higher quantities of ATP ? but solid tumor cells, which have little access to oxygen, are forced to rely almost exclusively on aerobic glycolysis for survival.
Zhou's study, published in Cancer Cell, showed that the powerful transcription factor complex Snail-G9a-Dnmt1 is over-expressed in triple-negative breast cancer, inhibiting the enzyme 1,6-bisphosphate (FBP1). The loss of this enzyme shuts down the glucose anabolic pathway and promotes the glucose catabolic pathway, leading to a large amount of glucose entering the tumor cells and thus "feeding" the aggressive cancer. This metabolic switch empowers the triple-negative breast cancer cells to suck more glucose from the body, increasing macromolecule biosynthesis in tumor cells and maintaining ATP production despite a dearth of nutrients and an oxygen-free environment.
Triple-negative breast cancer is the most deadly subtype of breast cancer, and tends to occur in women at a younger age. This subtype of breast cancer has poor clinical outcomes due to the early metastasis of tumor cells, resistance to chemotherapy, and the lack of specific drugs that target it. Identifying this change in the cancer's metabolic process provides major insight into developing drugs to target the disease, Zhou says.
"These findings present significant insights regarding the development and progression of triple-negative breast cancer," said Zhou, associate professor of molecular and cellular biochemistry at UK. "They indicate that targeting the metabolic alteration will lead to an effective approach for treating this deadly disease."
Zhou's research was aided by the team in the Free Radical Biology in Cancer Shared Resource Facility (FRBC) of the Markey Cancer Center, directed by Dr. Allan Butterfield. The FRBC used an instrument called the Seahorse XF-96 Flux Analyzer to test and confirm the predictions of Zhou's findings in triple-negative breast cancer.
"The significance of this study rests in proving that triple negative breast cancer cells utilize glycolysis for survival and growth," Butterfield said. "The FRBC will assist Dr. Zhou in furthering this exciting research, potentially helping to identify key proteins in triple negative breast cancer cells that are expressed or modified differently than in control cells. Such knowledge may lead to new insights to potential approaches to treat this aggressive cancer."
###
University of Kentucky: http://www.uky.edu
Thanks to University of Kentucky for this article.
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Autodesk's been trying to bring its special effects expertise to bear on various handheld apps, and now its turning to cameras with its first release of Socialcam (version 5), since it bought the app last July. With the release, it's bringing updated visual effects, 720P resolution, HDR video with one-click mapping, color correction and a new logo to the to the app's estimated 20 million users. You'll be able to grab it gratis for iOS at the App Store today, or on Play for Android at an unspecified date next week. We're not sure if future releases will include the ability to add creatures to your vacation snaps, but we can always dream.
Feb. 28, 2013 ? Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway. In the horseradish leaf beetle Phaedon cochleariae a single enzyme can trigger the production of two completely different substances depending on whether it is regulated by cobalt, manganese or magnesium ions: iridoids, which are defensive substances the larvae use to repel predators, or juvenile hormones, which control insect's development. Insects unlike plants do not have a large arsenal of the proteins called isoprenyl diphosphate synthases. Therefore they may have developed another efficient option to channel metabolites into the different directions of terpenoid metabolism by using metal ions for control.
Natural products: 40,000 terpenes
Apart from the primary metabolism which produces substances that ensure the survival of the cells, there are additional biosynthetic pathways in all organisms. Their products may be less important for a single cell, but they can nevertheless be essential for the whole organism. These pathways are summarized as secondary metabolism. One of them is the terpenoid pathway: with more than 40,000 different known structures it generates one of the largest classes of natural products. Terpenoid molecules have diverse functions and can act as components in molecular signaling pathways, as toxins, fragrances or hormones.
The basic unit of all terpenes is a simple molecule containing five carbon atoms that can be joined to chains of different length. There are monoterpenes (C10 units, 2 x C5), sesquiterpenes (C15, 3 x C5), and even polymers, such as natural rubber, which comprises several hundred C5 units. Special enzymes mediate chain elongation. These enzymes have attracted the curiosity of scientists at the Max Planck Institute for Chemical Ecology, Jena, and the Leibniz Institute for Plant Biochemistry in Halle. They studied mechanistic alternatives of how chain elongation is regulated.
Metal ions instead of specialized enzymes
Enzymes involved in chain elongation belong to the group of isoprenyl diphosphate synthases. Such an enzyme was isolated from larvae of the horseradish leaf beetle Phaedon cochleariae. It raised the interest of Antje Burse, project group leader in the Department of Bioorganic Chemistry at the Max Planck Institute for Chemical Ecology.
Experiments with larvae in which the enzyme encoding gene was silenced showed that the protein was involved in the formation of the C10 monoterpene chrysomelidial that larvae produce to defend themselves against predators. The larvae accumulate this monoterpene in special glands and release it as a defensive secretion when they are attacked by their enemies, such as ants.
However, surprising results emerged after comprehensive biochemical characterization of the enzyme. "After we had conducted an in vitro analysis of the protein, including measurements of product formation in the presence of different metal ions as co-factors, we were surprised to discover that only geranyl diphosphate (C10), a precursor for the defensive substance chrysomelidial, was produced after addition of cobalt and manganese ions. On the other hand, adding magnesium ions resulted in the formation of farnesyl diphosphate (C15), a potential precursor for juvenile hormones, which is 5 carbon atoms longer," says the scientist. All three metals were found in larval tissue, leading to the assumption that enzyme catalysis is directed by the different metal co-factors in the larvae, whichever is predominant in amount: Towards toxin or hormone ? physiologically a major difference.
Sequence comparisons cannot replace a thorough biochemical analysis
How the different metal ions modify the product range of the enzyme is still unclear. It is very likely that the varying atomic radii of the metal ions involved in the catalysis effect changes in the spatial structure of the enzyme, which prevent or allow the admission of a third C5 unit and hence result in the production of C10 or C15 molecules.
"Our experiments provide two important findings," says Wilhelm Boland, director at the Max Planck Institute. "First, the directing influence of metal ions on the product formation of isoprenyl diphosphate synthases is a novel "control element" in the regulation of the terpene metabolism which should be included in future experimental settings. And secondly: The diversity of terpenoid molecules cannot be attributed solely to the broad substrate specificity of some enzymes in the last steps of the metabolic pathway, but is in fact already inherent in early biosynthetic steps." Nature continues to provide interesting answers to the question how organisms manage to produce tens of thousands of different secondary metabolites.
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The above story is reprinted from materials provided by Max Planck Institute for Chemical Ecology.
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Journal Reference:
S. Frick, R. Nagel, A. Schmidt, R. R. Bodemann, P. Rahfeld, G. Pauls, W. Brandt, J. Gershenzon, W. Boland, A. Burse. Metal ions control product specificity of isoprenyl diphosphate synthases in the insect terpenoid pathway. Proceedings of the National Academy of Sciences, 2013; DOI: 10.1073/pnas.1221489110
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Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
Contact: Joseph Winters joseph.winters@iop.org 020-747-04815 Institute of Physics
Anil Ananthaswamy has won the inaugural Physics Journalism Prize a prize designed to inspire the next generation of physicists by encouraging journalists to grapple with often complex topics and help spread excitement about the subject.
Anil has won the prize for his article Hip Hip Array, which focuses on the Square Kilometre Array, an international project to design and build the largest radio telescope ever conceived.
The prize is sponsored by the Institute of Physics (IOP) and the Science and Technology Facilities Council (STFC).
Anil, a consultant at New Scientist Magazine and author of The Edge of Physics, will be congratulated today, Thursday 28 February 2013, at an IOP reception this evening in Central London, which follows this year's Newton Lecture by the Astronomer Royal, Lord Rees of Ludlow, entitled From Mars to the Multiverse.
Professor Sir Peter Knight, President of IOP, said, "Anil Ananthaswamy is being awarded the prize for writing a feature which brings one of the world's most exciting astronomical endeavours to life the Square Kilometre Array.
"I'm delighted that we're able to honour his writing on this occasion, shortly after we hear from one of the UK's leading astronomical luminaries."
The Physics Journalism Award offers the prize of an expenses paid trip to Japan, to visit world-leading facilities carrying out research at the frontiers of physics.
On winning, Anil commented, "Writing about physics, especially about the work being done in remote, difficult and sometimes hostile environments, is a special pleasure. Winning an award for doing what I love to do is just icing on the cake. I truly appreciate the recognition."
With Anil the overall winner, judges were impressed by the range of entries made to the Award.
Zeeya Merali, a freelance science journalist based in Canterbury, has been given a special mention and a 250 prize for her Discover article, Gravity Off the Grid; an article about Julian Barbour, a British physicist who has spent his life arguing against Einstein's view of gravity, space and time.
The judges who were the Association of British Science Writers' (ABSW) Martin Ince, the Wellcome Trust's Mark Henderson, STEMNET's Kirsten Bodley and the Science Media Centre's Ed Sykes - commended both of the journalists for style, their ability to inspire and for bringing the physics that they write about to life.
ABSW director Martin Ince said, "The judges awarded the first prize and the commendation to two very different, but equally compelling, pieces of writing about physics. Both will have inspired and intrigued readers in the UK and around the world. The entries we received show that British science journalists can take on some of the most complex subjects in the universe and bring them to a wide audience."
Mark Henderson, Head of Communications at the Wellcome Trust and former Science Editor at The Times, said, "This was a strong field, but the winning and commended entries stood out both for style and substance. Zeeya Merali crafts great metaphors that help to make complicated science comprehensible for non-specialist audiences, while Anil Ananthaswamy has an eye for illustrative detail of which the best travel writers would be proud."
Kirsten Bodley, Chief Executive of STEMNET, said, "The winning article on the competition for the Square Kilometre Array will be particularly inspirational to young people, offering them an opportunity to see how fascinating contemporary physics research can be. This is close to STEMNET's heart it's important to make science accessible and interesting for young people, to inspire the next generation of great British scientists and engineers."
Commenting on the winner's choice of topic, Terry O'Connor, Head of Communications at STFC, added, "The Square Kilometre Array will be one of the world's largest and most complex science experiments, requiring physics input across the disciplines and at every stage of its design, construction and operation. It will open new avenues of research, and delve further back into the formation of the universe.
"With the SKA Project Office located in the UK at Jodrell Bank, and UK researchers and government heavily involved at every stage, we're delighted that the winning article highlighted this fascinating and ambitious project."
###
Anil's article can be read on newscientist.com, free of charge but after a short registration, at http://www.newscientist.com/article/mg21328576.800-outback-to-outer-space-the-worlds-largest-telescope.html
Zeeya's article can be read on discovermagazine.com, free of charge at
To revisit the Terms and Conditions of the Award, please go to http://www.stfc.ac.uk/News%20and%20Events/39891.aspx
3. The Institute of Physics
The Institute of Physics is a leading scientific society. We are a charitable organisation with a worldwide membership of more than 45,000, working together to advance physics education, research and application.
We engage with policymakers and the general public to develop awareness and understanding of the value of physics and, through IOP Publishing, we are world leaders in professional scientific communications. Visit us at www.iop.org
4. The Science and Technology Facilities Council
The Science and Technology Facilities Council is keeping the UK at the forefront of international science and tackling some of the most significant challenges facing society such as meeting our future energy needs, monitoring and understanding climate change, and global security.
The Council has a broad science portfolio and works with the academic and industrial communities to share its expertise in materials science, space and ground-based astronomy technologies, laser science, microelectronics, wafer scale manufacturing, particle and nuclear physics, alternative energy production, radio communications and radar.
STFC operates or hosts world class experimental facilities including:
in the UK; ISIS pulsed neutron source, the Central Laser Facility, and LOFAR. STFC is also the majority shareholder in Diamond Light Source Ltd
overseas; telescopes on La Palma and Hawaii
It enables UK researchers to access leading international science facilities by funding membership of international bodies including European Laboratory for Particle Physics (CERN), the Institut Laue Langevin (ILL), European Synchrotron Radiation Facility (ESRF) and the European Southern Observatory (ESO).
STFC is one of seven publicly-funded research councils. It is an independent, non-departmental public body of the Department for Business, Innovation and Skills (BIS).
Follow us on Twitter @STFC_Matters
www.stfc.ac.uk
5. Association of British Science Writers
Founded in 1947, the Association of British Science Writers (ABSW) is the professional organisation for science writers in the UK. Its 800 members write everything from news stories to books and TV programmes. It runs the UK's science journalism awards, holds the UK Conference of Science Journalists, and helps entrants to the profession to expand their skills. It is a leading member of the World Federation of Science Journalists and is involved in promoting science journalism in the developing world. More at http://www.absw.org.uk/.
[ | E-mail | Share ]
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Joseph Winters joseph.winters@iop.org 020-747-04815 Institute of Physics
Anil Ananthaswamy has won the inaugural Physics Journalism Prize a prize designed to inspire the next generation of physicists by encouraging journalists to grapple with often complex topics and help spread excitement about the subject.
Anil has won the prize for his article Hip Hip Array, which focuses on the Square Kilometre Array, an international project to design and build the largest radio telescope ever conceived.
The prize is sponsored by the Institute of Physics (IOP) and the Science and Technology Facilities Council (STFC).
Anil, a consultant at New Scientist Magazine and author of The Edge of Physics, will be congratulated today, Thursday 28 February 2013, at an IOP reception this evening in Central London, which follows this year's Newton Lecture by the Astronomer Royal, Lord Rees of Ludlow, entitled From Mars to the Multiverse.
Professor Sir Peter Knight, President of IOP, said, "Anil Ananthaswamy is being awarded the prize for writing a feature which brings one of the world's most exciting astronomical endeavours to life the Square Kilometre Array.
"I'm delighted that we're able to honour his writing on this occasion, shortly after we hear from one of the UK's leading astronomical luminaries."
The Physics Journalism Award offers the prize of an expenses paid trip to Japan, to visit world-leading facilities carrying out research at the frontiers of physics.
On winning, Anil commented, "Writing about physics, especially about the work being done in remote, difficult and sometimes hostile environments, is a special pleasure. Winning an award for doing what I love to do is just icing on the cake. I truly appreciate the recognition."
With Anil the overall winner, judges were impressed by the range of entries made to the Award.
Zeeya Merali, a freelance science journalist based in Canterbury, has been given a special mention and a 250 prize for her Discover article, Gravity Off the Grid; an article about Julian Barbour, a British physicist who has spent his life arguing against Einstein's view of gravity, space and time.
The judges who were the Association of British Science Writers' (ABSW) Martin Ince, the Wellcome Trust's Mark Henderson, STEMNET's Kirsten Bodley and the Science Media Centre's Ed Sykes - commended both of the journalists for style, their ability to inspire and for bringing the physics that they write about to life.
ABSW director Martin Ince said, "The judges awarded the first prize and the commendation to two very different, but equally compelling, pieces of writing about physics. Both will have inspired and intrigued readers in the UK and around the world. The entries we received show that British science journalists can take on some of the most complex subjects in the universe and bring them to a wide audience."
Mark Henderson, Head of Communications at the Wellcome Trust and former Science Editor at The Times, said, "This was a strong field, but the winning and commended entries stood out both for style and substance. Zeeya Merali crafts great metaphors that help to make complicated science comprehensible for non-specialist audiences, while Anil Ananthaswamy has an eye for illustrative detail of which the best travel writers would be proud."
Kirsten Bodley, Chief Executive of STEMNET, said, "The winning article on the competition for the Square Kilometre Array will be particularly inspirational to young people, offering them an opportunity to see how fascinating contemporary physics research can be. This is close to STEMNET's heart it's important to make science accessible and interesting for young people, to inspire the next generation of great British scientists and engineers."
Commenting on the winner's choice of topic, Terry O'Connor, Head of Communications at STFC, added, "The Square Kilometre Array will be one of the world's largest and most complex science experiments, requiring physics input across the disciplines and at every stage of its design, construction and operation. It will open new avenues of research, and delve further back into the formation of the universe.
"With the SKA Project Office located in the UK at Jodrell Bank, and UK researchers and government heavily involved at every stage, we're delighted that the winning article highlighted this fascinating and ambitious project."
###
Anil's article can be read on newscientist.com, free of charge but after a short registration, at http://www.newscientist.com/article/mg21328576.800-outback-to-outer-space-the-worlds-largest-telescope.html
Zeeya's article can be read on discovermagazine.com, free of charge at
To revisit the Terms and Conditions of the Award, please go to http://www.stfc.ac.uk/News%20and%20Events/39891.aspx
3. The Institute of Physics
The Institute of Physics is a leading scientific society. We are a charitable organisation with a worldwide membership of more than 45,000, working together to advance physics education, research and application.
We engage with policymakers and the general public to develop awareness and understanding of the value of physics and, through IOP Publishing, we are world leaders in professional scientific communications. Visit us at www.iop.org
4. The Science and Technology Facilities Council
The Science and Technology Facilities Council is keeping the UK at the forefront of international science and tackling some of the most significant challenges facing society such as meeting our future energy needs, monitoring and understanding climate change, and global security.
The Council has a broad science portfolio and works with the academic and industrial communities to share its expertise in materials science, space and ground-based astronomy technologies, laser science, microelectronics, wafer scale manufacturing, particle and nuclear physics, alternative energy production, radio communications and radar.
STFC operates or hosts world class experimental facilities including:
in the UK; ISIS pulsed neutron source, the Central Laser Facility, and LOFAR. STFC is also the majority shareholder in Diamond Light Source Ltd
overseas; telescopes on La Palma and Hawaii
It enables UK researchers to access leading international science facilities by funding membership of international bodies including European Laboratory for Particle Physics (CERN), the Institut Laue Langevin (ILL), European Synchrotron Radiation Facility (ESRF) and the European Southern Observatory (ESO).
STFC is one of seven publicly-funded research councils. It is an independent, non-departmental public body of the Department for Business, Innovation and Skills (BIS).
Follow us on Twitter @STFC_Matters
www.stfc.ac.uk
5. Association of British Science Writers
Founded in 1947, the Association of British Science Writers (ABSW) is the professional organisation for science writers in the UK. Its 800 members write everything from news stories to books and TV programmes. It runs the UK's science journalism awards, holds the UK Conference of Science Journalists, and helps entrants to the profession to expand their skills. It is a leading member of the World Federation of Science Journalists and is involved in promoting science journalism in the developing world. More at http://www.absw.org.uk/.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
NEW YORK (AP) ? The breakup of the Big East's football and basketball schools appears to be on the fast track.
The major college football members will meet in Atlanta on Friday to discuss the departure of the seven basketball schools that are planning to leave the conference and create a new league.
According to media reports Thursday, the basketball schools plan to have their new conference up and running for the 2013-14 school year and will pay the football schools to keep the Big East name and play its conference tournament at Madison Square Garden in New York.
Big East Commissioner Mike Aresco told the AP in a phone interview no deal has been completed between the two groups but "some of this stuff is clearly coming down to the wire."
Aresco will be meeting with the presidents and athletic directors from the football members. The members that do not have FBS football programs will not be part of the meeting.
The seven Catholic schools that are breaking away from the football part of the rebuilt Big East include some of its founding members and signature schools, such as Georgetown, St. John's and Villanova. The other departing schools are Seton Hall, Providence, DePaul and Marquette.
Big East football is in the midst of a major makeover, with 2013 scheduled to be another season with lame duck members.
Next year, Big East football will have holdovers Connecticut, Cincinnati, South Florida, Temple, Rutgers and Louisville, along with newcomers Central Florida, Memphis, Houston and SMU.
In 2014, Louisville and Rutgers are likely on the way out ? the Cardinals to the Atlantic Coast Conference and the Scarlet Knights to the Big Ten ? and Tulane and East Carolina will join. Navy is schedule to join the Big East for football in 2015, and the conference is looking to add another member ? Tulsa is the front-runner ? to get to an even 12.
The Big East is also putting the finishing touches on a new TV deal with ESPN.
The network last week matched an offer made by NBC for the TV rights to the conference. The deal will be for seven years and pay the league about $130 million, though that figure would come down if the seven Catholic schools are not in the league next season.
It had been presumed that the seven basketball schools would stay in the current Big East for another year, because time is getting tight to start a new conference. But with a TV deal reportedly waiting for them, it seems they're ready to ramp up the process.
The seven basketball schools reportedly have an offer from Fox to broadcast its games that could earn the schools about $3 million per year, depending on how many more members they bring on. Butler, Xavier and Creighton are being talked about as potential targets.
A faster-than-expected divorce between Big East football and basketball puts Notre Dame in an uncertain situation.
The Fighting Irish have announced they will leave the Big East and join the ACC in everything but football and hockey, but no timetable has been set for their departure.
Notre Dame athletic director Jack Swarbrick has said that he expected the Irish to stay in the Big East through next season. But what does that mean if the Big East is now the basketball-only schools?
A phone message left for Swarbrick was not immediately returned Thursday night.
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Public release date: 28-Feb-2013
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